Bioinformatics applied to gene transcription regulation

Applied Bioinformatics for Gene Characterization

Bioinformatics of Eukaryotic Gene Regulation

Understanding the mechanisms which control gene expression is one of the fundamental problems of molecular biology. Detailed experimental studies of regulation are laborious due to the complex and combinatorial nature of interactions among involved molecules. Therefore, computational techniques are used to suggest candidate mechanisms for further investigation. This thesis presents three method...

Bioinformatics applied to infectious diseases

Applied to the study of infectious diseases, bioinformatics permits a gene survey of related biological sequences, which consists of molecular characterization, structure prediction, phylogenetic analysis and regulatory motif prediction. Bioinformatics has also become an integral part of the investigation of the biological complexity of host-pathogen interactions. For example, the increasing nu...

Applied Bioinformatics

An introduction to transcription and gene regulation.

Having been offered the opportunity to contribute one of the episodes of this series of personal-history accounts, I have chosen to write about circumstances that led me to the start of the scientific path that I have followed for the past 40-odd years. My account deals with a period of approximately six years and with events that I have written about recently (1); while I have been conscientio...